The Food and Drug Administration (FDA) approved an over-the-counter version of the fat-blocking diet drug Xenical last week, making it the first FDA approved weight loss product available without a prescription.
The drug will be sold under the brand name Alli and will contain about half the amount of the fat-blocking drug orlistat than the prescription version contains.
GlaxoSmithKline, the company that manufacturers the pill, expects the drug to be in stores by summer 2007.
Alli blocks the absorption of about 25 percent of the fat consumed when taken at meal times. The fat is then passed out of the body through stools and eliminates about 150 to 200 calories from fat.
Consuming a high-fat meal while using Alli can result in uncomfortable bowel changes such as loose stools or a sudden urge to use the bathroom, Brian Jones, vice president of communications for GlaxoSmithKline.
According to a press release, the recommended dose is one 60-milligram capsule, three times a day, with meals.
"It is about 60 cents a capsule," Jones said. "It is certainly affordable for most Americans. It's about the cost of a soda and a bag of chips."
The drug is intended for people 18 and older and because of the way it works, the company recommends that it be used in combination with a healthy lifestyle, exercise, and a reduced-calorie diet that contains about 15 grams of fat per meal.
"Essentially, you have to follow a low-calorie diet to be successful," Jones said. "It's not a magic pill that will cause you to lose weight in hours."
Users will lose weight steadily over time, Jones said.
Associate professor of nutritional neuroscience Rebecca Corwin said she is not an advocate of using drugs as a long-term solution for weight loss.
"I think they're okay in moderation," Corwin said. "The critical thing is that people have got to learn healthy habits if they're going to be successful in the long-term. That's the tough part."



