Courtney Coleman led Ohio State with 17 points and 13 rebounds, while Tomeka Brown added 12 for the Bucks. Mazzante finished with 18 points and nine steals for Penn State, senior forward Maren Walseth had 14 points and 10 boards and senior guard Lisa Shepherd added 13 points and four assists.
Penn State overcame 21 turnovers, 13 of them in the first half, to win for the fourth time in the last five games and keep their nine-game home winning streak intact.
"It's a physical game when you play them and everybody knows that," Penn State women's basketball coach Rene Portland said. "We did a better job in the second half of taking care of the basketball."
For the first time all season, Penn State did not convert a three-point field goal, but the Lions compensated by attacking the Buckeyes inside and pushing the ball up court for easy baskets in transition.
"We're not the kind of team that's going to rely on our three-point shot," Shepherd said. "If we're not hitting it then we have other options."
The Buckeyes didn't light it up from the outside either, or from anywhere for that matter. Ohio State shot an abysmal 3-14 from downtown and just 38 percent overall, compared to Penn State's 49 percent.
Ohio State women's basketball coach Beth Burns credited the Lions, who defeated the Buckeyes for the second time this season (Penn State won 66-63 in Columbus on New Year's Eve) with again being able to disrupt her team's offense.
"Penn State does a great job of doing a lot of different things and playing with aggression," she said. "We've struggled somewhat on the perimeter against that kind of stuff."
Portland said the streaking Lions are definitely headed in the right direction as they prepare to go on the road against Northwestern on Sunday (3 p.m., Welsh-Ryan Arena) and Michigan State next Thursday.
"I think everybody's learning their roles and they're playing better like a team," Portland said. "But they have to continue to play hard."