The twins are currently in the second phase of leukemia treatment, known as interim maintenance, Freiberg said. In March, Hope and Faith begin delayed intensification therapy, when they will be given large doses of chemotherapy drugs to kill any dormant leukemia cells remaining in the body, he said.
Though only three years old, the twins understand many of the procedures that are part of their treatments. Reciting the names of their medications and recognizing ones they described as "yucky," Hope and Faith present a knowledge of cancer that is surprising, given their age, Sandy Rapp said.
The twins have received their knowledge about cancer from the nurses of the Hershey Medical Center. The medical staff encourages Hope and Faith to have active roles in their treatments by explaining procedures and medicines to them.
During one of the twins' visits to Hershey, doctors performed a bone marrow test on Hope, Sandy Rapp said. Once she awoke from anesthesia, nurses allowed Hope and her sister to view cells from Hope's back under a microscope.
"When Hope could see that everyone was looking at her cells, she was proud," she said.
Though Hope and Faith's involvement in their medical therapy has helped to create a positive treatment environment for the girls, they still find some days exceptionally difficult.
Sandy Rapp said visits requiring shots are among the twins' least favorite. Treatments where anesthesia is used are also uncomfortable for the girls, Michael Rapp said.
"The twins have problems sometimes when they are partly put under," he said. "When they come out from under that medication, they act totally different than normal and that makes it really hard."
During the past four months, Hope and Faith have endured numerous doctor visits and procedures and have more intense treatments scheduled for March. As a mother, it is difficult to watch the twins go through the treatments, Sandy Rapp said. To help ease their discomfort, she mixes Hope's medicine with chocolate pudding and Faith's with strawberry syrup.
In addition to administering medicine with everything from pudding to peppermint patties, Sandy Rapp said she tries to make treatment days at the Hershey Medical Center special ones by giving the twins small gifts left over from those they received on Christmas. Despite her efforts to alleviate Hope and Faith's discomfort during their medical therapy, Rapp's intent is not to help the girls forget their experiences with cancer. To the contrary, a project she is working on may help them remember their days with cancer.
Sandy Rapp is keeping a journal of the twins' experiences so when they get older, they have a permanent record of their battle against and their hopeful victory over cancer. The journal, a witness to the twins' ongoing struggle, is a testimony of faith and hope for the Rapp family.